abstract：:The availability of resource (staffing and services) in all 21 paediatric diabetes services in Yorkshire and Humber Strategic Health Authority, UK was surveyed and this information was combined with demographic and clinical data on 2683 children and young people with diabetes (aged 0-23 years) to assess whether level ...

journal_title：Archives of disease in childhood

authors： Harron KL,McKinney PA,Feltbower RG,Holland P,Campbell FM,Parslow RC

更新日期：2012-06-01 00:00:00

abstract：:There is little high quality evidence on which to base the management of bone and joint infections in children. This pragmatic practice note aims to provide a consensus framework of best current practice prior to the availability of data from large national randomised controlled trials. For straightforward infection i...

journal_title：Archives of disease in childhood

authors： Faust SN,Clark J,Pallett A,Clarke NM

更新日期：2012-06-01 00:00:00

abstract：INTRODUCTION:Aerosol therapy in infants may be greatly compromised by face mask rejection due to squirming and crying. Lung aerosol deposition in crying infants may thereby be greatly reduced. Since 'suckling' on a pacifier calms infants, they should more readily accept a face mask that incorporates a pacifier. However...

journal_title：Archives of disease in childhood

authors： Amirav I,Luder A,Chleechel A,Newhouse MT,Gorenberg M

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:The isolated finding of an unexplained chronic subdural haematoma in an infant may suggest non-accidental head injury (NAHI). The authors report a previously undescribed cause of multifocal chronic subdural haematoma in infancy which could result in a misdiagnosis of previous NAHI. METHODS:Two infants, aged...

journal_title：Archives of disease in childhood

authors： Edwards RJ,Allport TD,Stoodley NG,O'Callaghan F,Lock RJ,Carter MR,Ramanan AV

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVES:To assess the potential effect of two guideline discharge oxygen saturation (SpO(2)) recommendations (≥90% and ≥94%) in recovering bronchiolitis. METHODS AND PATIENTS:Infants aged up to 18 months requiring therapeutic oxygen for SpO(2) (≤93%) had SpO(2) assessed in air every 2 h. Time from admission to re-e...

journal_title：Archives of disease in childhood

authors： Cunningham S,McMurray A

更新日期：2012-04-01 00:00:00

abstract：:The accuracies of chromogenic agar and the GeneXpert real-time PCR system (Cepheid, Sunnyvale, California, USA) for admission methicillin-resistant Staphylococcus aureus (MRSA) screening of 1336 consecutive paediatric intensive care unit patients (1282 evaluable swab results) were determined using enrichment culture a...

journal_title：Archives of disease in childhood

authors： Gray J,Patel M,Turner H,Reynolds F

更新日期：2012-03-01 00:00:00

abstract：:Encephalitis is an uncommon but potentially devastating neurological syndrome with different aetiologies including direct central nervous system infection with different agents (most commonly viral) and those mediated by the immune system. Whilst there have been several recent publications and guidelines on the manage...

journal_title：Archives of disease in childhood

authors： Thompson C,Kneen R,Riordan A,Kelly D,Pollard AJ

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:To characterise fetal brain growth in children with specific language impairment (SLI). DESIGN:A nested case-control study. SETTING:Perth, Western Australia. PARTICIPANTS:Thirty children meeting criteria for SLI at age 10 years were individually matched with a typically developing comparison child on sex, ...

journal_title：Archives of disease in childhood

authors： Whitehouse AJ,Zubrick SR,Blair E,Newnham JP,Hickey M

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Although antibiotics are recommended for the primary care management of community-acquired pneumonia, a recent UK study reported that most children admitted to hospital had not received antibiotics. OBJECTIVE:To describe primary care antibiotic use for children subsequently hospitalised with community-acqui...

journal_title：Archives of disease in childhood

authors： Grant CC,Harnden A,Mant D,Emery D,Coster G

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:To assess uptake of community-based capillary thyroid stimulating hormone (TSH) screening in Scotland and determine the optimal frequency of screening, the justification for preschool screening and strategies for treatment. METHODS:Subjects with Down's syndrome aged 1-19 years underwent capillary TSH measur...

journal_title：Archives of disease in childhood

authors： McGowan S,Jones J,Brown A,Reynolds L,Leyland K,Charleton P,Rahim M,Mansor M,Ritha S,Donaldson M,Scottish Down Syndrome Thyroid Screening Group.

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:To ascertain mortality from 1 to 18 years, and predictors of mortality. DESIGN:Long-term follow-up of population cohort born 1989-1992. SETTING:Births in South East Thames Region. PATIENTS:346 children with bilateral cerebral palsy (CP). INTERVENTIONS:Not applicable. MAIN OUTCOME MEASURES:Mortality; pred...

journal_title：Archives of disease in childhood

authors： Baird G,Allen E,Scrutton D,Knight A,McNee A,Will E,Elbourne D

更新日期：2011-11-01 00:00:00

abstract：AIMS:The Royal College of Paediatrics and Child Health (RCPCH) Science and Research Department was commissioned by the Department of Health to develop national care pathways for children with allergies: the asthma/rhinitis care pathway is the third such pathway. Asthma and rhinitis have been considered together. These ...

journal_title：Archives of disease in childhood

authors： Vance G,Lloyd K,Scadding G,Walker S,Jewkes F,Williams L,Dixon L,O'Beirne C,Fletcher P,Brown T,Hughes J,Sohi D,Piddock C,Shields M,McKean M,Warner J,Science and Research Department, Royal College of Paediatrics and Child H

更新日期：2011-11-01 00:00:00

abstract：:When children are considered for participation in research, British and international guidelines suggest that they should provide assent in addition to their parents' consent. However, examination of these guidelines shows there is confusion regarding the concept of assent. Furthermore, the need for assent may cause p...

journal_title：Archives of disease in childhood

authors： Baines P

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVES:To explore how parents navigate urgent and emergency care (U&EC) services when their child <5 years old has a feverish illness, their views of that experience and whether services are meeting their needs and triaging in line with national guidance. DESIGN:Parents of a febrile child <5 years old contacting a...

journal_title：Archives of disease in childhood

authors： Maguire S,Ranmal R,Komulainen S,Pearse S,Maconochie I,Lakhanpaul M,Davies F,Kai J,Stephenson T,RCPCH Fever Project Board.

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVES:To estimate the incidence of cystic-fibrosis-related diabetes (CFRD) in youth from New South Wales (NSW) and the Australian Capital Territory (ACT), Australia and to examine demographic/clinical features at diagnosis. METHODS:Incident cases of CFRD in young people aged ≤ 18 years diagnosed during 2000 to 20...

journal_title：Archives of disease in childhood

authors： Rana M,Munns CF,Selvadurai HC,Simonds S,Cooper PJ,Woodhead HJ,Hameed S,Verge CF,Lafferty AR,Crock PA,Craig ME

更新日期：2011-09-01 00:00:00

abstract：:Diseases causing high mortality in children under 5 years of age in resource limited settings (RLS) could be treated if children in these countries had access to existing medicines. It took 30 years before the WHO Essential Medicines List (EML) considered the issue of medicines for children, with the first EML for chi...

journal_title：Archives of disease in childhood

authors： Hoppu K,Sri Ranganathan S,Dodoo AN

更新日期：2011-08-01 00:00:00

abstract：:Fundamental to appropriate nutritional prescription is an understanding of the conditions necessary for growth that include the requirements for energy in health and illness. Energy requirements need to be met by the dietary intake to prevent weight loss. A positive energy balance will result in weight gain. Energy re...

journal_title：Archives of disease in childhood

authors： Wiskin AE,Davies JH,Wootton SA,Beattie RM

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:There are no objective ambulatory studies on the temporal relationship between reflux and cough in children. Commercial pHmetry loggers have slow capture rates (0.25 Hz) that limit objective quantification of reflux and cough. The authors aimed to evaluate if there is a temporal association between cough and ...

journal_title：Archives of disease in childhood

authors： Chang AB,Connor FL,Petsky HL,Eastburn MM,Lewindon PJ,Hall C,Wilson SJ,Katelaris PH

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:Infants who cry a lot, or are unsettled in the night, are common sources of concern for parents and costly problems for health services. The two types of problems have been linked together and attributed to a general disturbance of infant regulation. Yet the infant behaviours involved present differently, at ...

journal_title：Archives of disease in childhood

authors： St James-Roberts I,Peachey E

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:Congenital hypothyroidism (CHT) is a common cause of preventable mental retardation, and the quantification of intellectual disability due to CHT is needed to assess the public health benefit of newborn screening. DESIGN:Review of published studies conducted among children born prior to the introduction of n...

journal_title：Archives of disease in childhood

authors： Grosse SD,Van Vliet G

更新日期：2011-04-01 00:00:00

abstract：INTRODUCTION:Intravenous paracetamol (acetaminophen) has recently been registered for treatment of pain in neonates but the pharmacodynamics, including effects on body temperature, have not been reported. METHODS:A pooled analysis on body temperature recordings in neonates exposed to intravenous paracetamol was perfor...

journal_title：Archives of disease in childhood

authors： Hopchet L,Kulo A,Rayyan M,Verbesselt R,Vanhole C,de Hoon JN,Allegaert K

更新日期：2011-03-01 00:00:00

abstract：AIM:To determine whether emergency hospital admission rates (EAR) for common paediatric conditions in Greater London are associated with measures of child well-being and deprivation. DESIGN:Retrospective analysis of hospital episode statistics and secondary analysis of the Index of Multiple Deprivation (IMD) 2007 and ...

journal_title：Archives of disease in childhood

authors： Kyle RG,Kukanova M,Campbell M,Wolfe I,Powell P,Callery P

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:The European Respiratory Society guidance on bronchoalveolar lavage (BAL) in children was published in 2000. It recommended taking one BAL specimen from the most affected lobe or from the right middle lobe in diffuse disease. In 2007, the European Respiratory Society modified the recommendations for children...

journal_title：Archives of disease in childhood

authors： Gilchrist FJ,Salamat S,Clayton S,Peach J,Alexander J,Lenney W

更新日期：2011-03-01 00:00:00

abstract：:Epilepsy affects an estimated 10.5 million children worldwide, of whom 80% live in developing countries. The treatment gap is estimated at around 90% in the Lao People's Democratic Republic (Lao PDR). The present work analyses some of the reasons that could explain the low access to antiepileptic drugs (AED) for child...

journal_title：Archives of disease in childhood

authors： Barennes H,Sengkhamyong K,Sambany EM,Koffi PN,Chivorakul P,Empis G,Clavel S,Somphavong S,Wangkou N,Rajaonarivo C,Harimanana A

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:To explore the effect of research ethics, governance and consent requirements and recent reforms on UK-wide follow-up of children with congenital heart defects (CHD). DESIGN:Prospective cohort study. SETTING:UK National Health Service. PATIENTS:3897 children with CHD requiring intervention, or resulting in...

journal_title：Archives of disease in childhood

authors： Knowles RL,Bull C,Wren C,Dezateux C

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To develop a clinical algorithm to identify paediatric patients who should be offered HIV testing in a setting of moderate HIV prevalence and limited resources. METHODS:In a prospective cross-sectional study at Port Moresby General Hospital, Papua New Guinea, carers of inpatients were offered HIV testing and...

journal_title：Archives of disease in childhood

authors： Allison WE,Kiromat M,Vince J,Wand H,Cunningham P,Graham SM,Kaldor J

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:Poor condition at birth may impact on IQ, although its effect on other measures of neurodevelopment is unclear. The authors' aim was to determine whether infants receiving resuscitation after birth have reduced scores in measures of attention, memory and language skills or the need for educational support at ...

journal_title：Archives of disease in childhood

authors： Odd DE,Whitelaw A,Gunnell D,Lewis G

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Propylene glycol (PG) is an unintentional frequently administered solvent in neonates despite the fact that PG accumulation potentially results in hyperosmolarity, lactic acidosis and renal/hepatic toxicity. METHODS:Prospective evaluation of renal (diuresis, creatinaemia, sodium), metabolic (base excess, ...

journal_title：Archives of disease in childhood

authors： Allegaert K,Vanhaesebrouck S,Kulo A,Cosaert K,Verbesselt R,Debeer A,de Hoon J

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Rectal measurement is considered a gold standard in many healthcare systems for body temperature measurement in children. Although this method has several disadvantages, an ideal alternative thermometer has not yet been introduced. However tympanic and infrared skin thermometers are potential alternatives. ...

journal_title：Archives of disease in childhood

authors： Paes BF,Vermeulen K,Brohet RM,van der Ploeg T,de Winter JP

更新日期：2010-12-01 00:00:00

abstract：:Concerns have been expressed in recent years about the decline in children's clinical and biomedical research in the UK, and in the paediatric academic workforce. Here I consider the extent to which these concerns are justified, the sweeping changes that have taken place in research funding, governance and organisatio...

journal_title：Archives of disease in childhood

authors： Modi N

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Data on the efficacy and safety of long-acting β2-agonists (LABA) in children are limited, and current guidelines recommend that LABA always be used with inhaled corticosteroids (ICS). OBJECTIVE:To compare asthma control, assessed by rescue medications use, in children prescribed LABA and ICS as a fixed-dos...

journal_title：Archives of disease in childhood

authors： Elkout H,McLay JS,Simpson CR,Helms PJ

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To assess the risk of skin cancer in persons treated with neonatal phototherapy (NNPT) for jaundice. DESIGN:Retrospective cohort study. SETTING:Grampian Region, Scotland, UK. DATA SOURCE:Aberdeen Maternity and Neonatal Databank. NNPT exposure was abstracted from paper records spanning 1976-1990. Follow-up ...

journal_title：Archives of disease in childhood

authors： Brewster DH,Tucker JS,Fleming M,Morris C,Stockton DL,Lloyd DJ,Bhattacharya S,Chalmers JW

更新日期：2010-10-01 00:00:00

abstract：AIM:To assess the provision of UK paediatric and adolescent diabetes services and examine changes in service delivery since 2002. METHOD:Questionnaires were sent to the lead paediatric consultant from all paediatric and adolescent diabetes services (n=205). Questions were based on National Institute for Health and Cli...

journal_title：Archives of disease in childhood

authors： Gosden C,Edge JA,Holt RI,James J,Turner B,Winocour P,Walton C,Nagi D,Williams R,Matyka K

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Children receiving chemotherapy for acute lymphoblastic leukaemia (ALL) may be susceptible to skeletal morbidity. AIM:To determine the incidence and risk factors for skeletal morbidity in ALL children. PATIENTS AND METHODS:The medical records of all (n=186, boys=110) children presenting to a single centre ...

journal_title：Archives of disease in childhood

authors： Elmantaser M,Stewart G,Young D,Duncan R,Gibson B,Ahmed SF

更新日期：2010-10-01 00:00:00

abstract：:Previously, quality of formulations information provided for oral medications used in paediatric clinical trials published in 10 highly cited journals between 2002 and 2004 raised concerns. This short report explores if there was any subsequent improvement on how the formulations used in trials involving children <12 ...

journal_title：Archives of disease in childhood

authors： Pandit S,Shah U,Kirby DJ,Nunn T,Tuleu C

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:Search for evidence supporting target age, level of intervention and target values for low-density lipoprotein (LDL) cholesterol levels in children with familial hypercholesterolemia. DESIGN:Systematic review and meta-analysis. PubMed, Medline, CINAHL and Cochrane Reviews databases from 1966 to 2007 were sea...

journal_title：Archives of disease in childhood

authors： Lebenthal Y,Horvath A,Dziechciarz P,Szajewska H,Shamir R

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To describe current practice during stabilisation of children presenting with critical illness to the district general hospital (DGH), preceding retrieval to intensive care. DESIGN:Observational study using prospectively collected transport data. SETTING:A centralised intensive care retrieval service in Eng...

journal_title：Archives of disease in childhood

authors： Lampariello S,Clement M,Aralihond AP,Lutman D,Montgomery MA,Petros AJ,Ramnarayan P

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:The effect of adenoidectomy on nasopharyngeal colonisation of pathogens has not previously been evaluated. The authors studied the effect of adenoidectomy on nasopharyngeal colonisation by bacteria causing otitis media and the effect of adenoidectomy on the development of pneumococcal capsular polysaccharide ...

journal_title：Archives of disease in childhood

authors： Mattila PS,Hammarén-Malmi S,Saxen H,Kaijalainen T,Käyhty H,Tarkkanen J

更新日期：2010-09-01 00:00:00

abstract：:This study compared the availability and the licensing status of analgesic drugs marketed in three European countries (Italy, France and the UK) and evaluated the evidence on safety and efficacy in the paediatric population of the drugs reported in the European Medicines Evaluation (EMA) document "Assessment of Pediat...

journal_title：Archives of disease in childhood

authors： Fortinguerra F,Maschi S,Clavenna A,Bonati M

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Timing of referral to subspecialists may be a major determinant for access to adequate treatment. Kidney transplantation is the preferred modality of renal replacement therapy (RRT) in children. In adults, delayed referral from general physicians to nephrologists reduced access to kidney transplantation. Thi...

journal_title：Archives of disease in childhood

authors： Boehm M,Winkelmayer WC,Arbeiter K,Mueller T,Aufricht C

更新日期：2010-08-01 00:00:00